CNLab Clinical Nanobiochemistry Laboratory, Department of Medicine and Surgery
Staff: Prof. Francesca Re_PA (Scopus ID: 36865029800); Dr. M. Silvia Sesana (PTA)
Non permanent staff: 4 PhD students
RESEARCH TOPICS
- Design of biotech nanosized systems for the therapy of central nervous system diseases;
- Design of biomimetic and bio-inspired systems for diagnosis and therapy of human disorders;
- Advanced in vitro cellular models of biological barriers;
- Gene therapy for human diseases
PROJECTS
- Nanoformulated oxytocin for brain targeting: potential therapeutic approach for neurodevelopmental disorders (NOXY4B); MUR, PRIN 2022;
- Development of gene therapy and RNA-based drug technologies; NRRP – National Centers CN3
- Dissecting the tumour-immune landscape of ccRCC: the role of altered lipid metabolism in resistance to immunotherapy; AIRC MFAG 2024
- CO2: from a global problem to a Tool to implement circularity CO-Tool (CO-Tool); FESR 2021-2027 (Bando Collabora & Innova)
LAB EQUIPMENT
- SYNTHESIS OF NANOPARTICLES:
- Lipex® liposome extruders (Evonik Industries AG)
- PURIFICATION PROCESSES:
- Ultracentrifuga Optima L-90 (Beckman)
- CHARACTERIZATION
- DLS – Dinamic light scattering – ZetaPlus (Brookhaven 90Plus Particle Size Analyzer, Zeta Potential Analyzer)
- Nanoparticle Tracking Analyzer (NanoSight NS300, Malvern)
- High Performance Liquid Chromatography (HPLC, 1260 Infinity II, Agilent)
- Spettrofluorimetro FP8500 Jasco
- BIOLOGICAL AND CELLULAR STUDIES
- FACILITIES
- Operetta CLS High-Content Analysis System – Perkin Elmer
CONTACT
e.mail: francesca.re1@unimib.it
website: https://www.cnlab.medicina.unimib.it/home;
instagram: @cnlab_