A short list of the main UNIMIB’s coordinated projects directly related to nanomedicine is reported below:

  • BASIC RESEARCH
    The purpose of this program is to combine chemical and physical innovative strategies for the preparation of new nanostructured materials for biomedical use, with high biocompatibility / biomimicry, highly specific targeting, relative easiness of preparation and low cost of production.
    • Design and Synthesis of NPs
    • Characterization (physicochemical, biological)
    • Nanomechanics of biological macromolecules and supramolecular aggregates
    • Innovative strategies for the synthesis and functionalization of nano- and micro-particles for biomedical use
  • NANOMEDICINE FOR THERAPY OF CANCER
    • Development of advanced Nanomedicines for treatment of cancer
    • Screening of anticancer chemotherapeutic drugs via nanoscale techniques
    • Nanotechnologies for the treatment of glioblastoma
  • NANOMEDICINE FOR BRAIN DISEASES
    • Nanotechnologies for therapy and diagnosis of neurodegenerative diseases -Parkinson, Alzheimer, SLA
    • Nanotechnology to overcome the blood-brain barrier
  • TOXICOLOGY OF NANOPARTICLES FOR MEDICAL USE                                                                                                                                                                                                                     The aim of the project, is to address, in a comprehensive and coordinated effort, the impact on human health of nano-particles including nano-pollutants emitted into environments.
    • Evaluation of the bio-safety of nano-particulate materials on in vitro and in vivo models
    • 3D optical sectioning of thick tissues for in-vivo studies
  • NANOTECHNOLOGY IN DIAGNOSTICS
    The aim of the project, is to design particles fulfill several criteria such as: high resolution, accuracy and sensitivity of detection, prolonged circulation time, target selectivity.
    • Novel hybrid magnetic nano-particles as MRI contrast agent
  • NANOTECHNOLOGIES IN REGENERATIVE MEDICINE
    • Design of materials for generation of Extracellular scaffolds and mimicking  human tissues
    • Organ-on-chip, 3D printinG
  • COMPUTATIONAL NANOMEDICINE
    • Design of novel bioinorganic nanoconjugates for improved drug delivery, targeting, imaging and cancer therapy
    • Multiscale modeling and dynamical simulation of nanosystems in biological media or across biomembrane models